Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

In this study, two human bocaviruses (HBoV), HBoV2 and HBoV3, that were detected previously in enteric samples were characterized genetically. Nearly complete genome sequences of three HBoV2 variants and one HBoV3 variant originating from Thailand and the UK were compared to published HBoV sequences. HBoV2 showed divergence from HBoV1 throughout the genome, while the HBoV3 sequence grouped phylogenetically with HBoV1 in the non-structural region and with HBoV2 sequences in the structural gene, consistent with its proposed recombinant origin. Compared to HBoV1 and HBoV3, HBoV2 shows substantially greater intra-species diversity, consistent with a longer period of human circulation.

Original publication

DOI

10.1007/s00705-010-0781-2

Type

Journal article

Journal

Arch Virol

Publication Date

12/2010

Volume

155

Pages

2023 - 2028

Keywords

Cluster Analysis, DNA, Viral, Genome, Viral, Human bocavirus, Humans, Molecular Sequence Data, Phylogeny, Sequence Analysis, DNA, Sequence Homology, Thailand, United Kingdom, Viral Nonstructural Proteins, Viral Structural Proteins