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Ganciclovir has been shown to be effective against cytomegalovirus (CMV) in vitro, but its role in the treatment of congenital cytomegalovirus infection is unknown. We describe its use in the management of two cases of congenital CMV infections. The drug was well tolerated and virus shedding in the urine was eliminated, though hepatosplenomegaly and neurodevelopmental delay persisted in both cases.

Original publication

DOI

10.3109/00365549309008515

Type

Journal article

Journal

Scand J Infect Dis

Publication Date

1993

Volume

25

Pages

385 - 388

Keywords

Cytomegalovirus Infections, Ganciclovir, Humans, Infant, Infant, Newborn, Infusions, Intravenous, Male, Recurrence