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This mini-review focuses on recent research with avian TLRs (Toll-like receptors), highlighting shared and distinct features compared with the more intensively studied mammalian TLR. These include the avian TLR repertoire and the response to various agonists. Studies with avian TLR can be applied to development of new approaches to control diseases of birds and is especially relevant to bird-borne zoonoses including avian influenza, Salmonella and Campylobacter.

Original publication

DOI

10.1042/BST0351504

Type

Journal article

Journal

Biochem Soc Trans

Publication Date

12/2007

Volume

35

Pages

1504 - 1507

Keywords

Amino Acid Sequence, Animals, Bird Diseases, Chickens, Conserved Sequence, Humans, Toll-Like Receptors, Zoonoses