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Childhood malaria remains a major killer in developing countries. Impregnated bednets could reduce the burden of disease now while vaccines are awaited. Recent studies on pathogenesis emphasise the systemic nature of severe disease even in African children and indicate that cerebral malaria is unlikely to be a homogenous syndrome. A broad, individualized approach to treatment is therefore required rather than merely the administration of antimalarial drugs. In regard to the latter, where quinine resistance is rare the use of newer quinghaosu derivatives confers no significant benefit.

Original publication




Journal article


Current Opinion in Infectious Diseases

Publication Date





221 - 225