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The genetic diversity of porB genes from meningococcal isolates characterized as serotype 22 was investigated by gene sequencing. This procedure identified seven distinct porB sequences, demonstrating variation in the PorB protein recognized by the serotype 22 monoclonal antibody. This is consistent with the genetic heterogeneity of serotype 22 meningococci reported previously.

Type

Journal article

Journal

J Clin Microbiol

Publication Date

12/1998

Volume

36

Pages

3680 - 3682

Keywords

Amino Acid Sequence, Bacterial Outer Membrane Proteins, Molecular Sequence Data, Neisseria meningitidis, Porins, Serotyping