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Parvovirus B19 is a common human pathogen which can cause severe syndromes, including aplastic anemia and fetal hydrops. The mapping of the first parvovirus B19-derived CD8(+) T-lymphocyte epitope is described. This HLA-B35-restricted peptide derives from the nonstructural (NS1) protein and is strongly immunogenic in B19 virus-seropositive donors.

Original publication

DOI

10.1128/JVI.75.1.540-543.2001

Type

Journal article

Journal

J Virol

Publication Date

01/2001

Volume

75

Pages

540 - 543

Keywords

CD8-Positive T-Lymphocytes, HLA-B35 Antigen, Humans, Leukocyte Common Antigens, Parvovirus B19, Human, Viral Nonstructural Proteins